Lorenzo Musetti vs. Novak Djokovic Picks and Predictions

Lorenzo Musetti vs. Novak Djokovic predictions

Our Lorenzo Musetti vs. Novak Djokovic predictions for Tuesday’s Men’s Australian Open match come down to one simple thing: pressure.

Djokovic puts constant pressure on your serve, especially your second serve.

Musetti already walks a fine line there, and against Djokovic, that line gets very thin real fast.

Add in the fact that Djokovic is fresher after skipping the Round of 16, and this sets up as a match that can get separated quickly if Musetti falls behind early.

Read on for my Lorenzo Musetti vs. Novak Djokovic predictions and picks for Tuesday, January 27.

Lorenzo Musetti vs. Novak Djokovic Breakdown

When Novak Djokovic is healthy and rested, he turns matches like this into return clinics.

He steps inside the court on second serves, takes time away, and immediately forces defense.

Lorenzo Musetti’s second serve is one of the weaker ones among elite tour players, and that’s where this matchup usually breaks open.

Musetti needs rhythm, time, and variety. Djokovic gives him none of that.

Points start on Djokovic’s terms, rallies stay neutral, and Musetti is forced to hit extra balls from uncomfortable positions. That’s how service games slip away, and sets get stretched.

Djokovic also comes in fresher after not playing a Round of 16 match. That matters here. It means sharper movement, better timing on returns, and no need to conserve energy if rallies extend.

Best Bets

Under 39.5 Games (-110)
This number leaves room for one competitive set while still cashing if Djokovic handles this in straight sets. If Djokovic gets early breaks, games disappear quickly.

Musetti needs multiple long sets to push this Over the total, and that’s a big ask given the return pressure he’ll face from the 10-time former Australian Open champion.

Djokovic -4.5 Games (-110)
Djokovic doesn’t need a blowout to cover this. One break per set often does it. If Musetti’s first-serve percentage dips, holding serve against arguably the greatest returner of all-time becomes a real problem.

Final Take

These Lorenzo Musetti vs. Novak Djokovic predictions aren’t complicated. Djokovic attacks second serves, controls the middle of the court, and closes without letting the match drift. If Musetti doesn’t start fast, this stays on Djokovic’s racquet and ends without drama.

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